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Pulmonary Acoustics In Excised Lung

The study of pulmonary acoustics in preserved pig lungs helps evaluate the computational acoustic model.

Experimental setup of SLDV
measurement of lung surface motion.

Experiment Setup

Simulation & Experimental Validation

Finite element (FE) simulation of sound transmission in the pig lung was conducted in Comsol 4.3a. Lung and airway geometry was constructed from CT scan image segmentation.

simple and complex airways
Lung and airway FE mesh
Lung and Airway FE mesh
Simple (left) and complex (right) airways.

Lung normal surface velocity magnitude (dB m/s for 1 Pa input acoustic pressure)

The following are three examples of experiment (b) simulation, lung with simple airway (c)simulation, lung with complex airway (d) Animation of experimental measurements

300 Hz
500 Hz
800 Hz

Simulation of real part of airway acoustic pressure (Pa) at 300, 500 and 800 Hz:
(a) Simple airways
(b) Complex airways

Stacked horizontal slices of the real part of the lung velocity in the anterior- posterior direction and airway acoustic pressure at 300, 500, and 800 Hz by simulation. (a) lung with simple airway (b) lung with complex airway

300 Hz
500 Hz
800 Hz

Simulation of sound transmission in lung with tumor

300 Hz

Simulation of shear wave propagation on normal and fibrotic lung

500 Hz
800 Hz

Cross-section Images of the real part of the lung velocity in the anterior-posterior direction (see arrow) in mm/s (a) normal lung, (b) fibrotic lung.

Fibrosis increases the lung shear stiffness, thus larger shear wave length is visualized in the fibrotic lung.